Megadose AI progress, ranked and analyzed.

OPERA: Offline Policy-guided Expert Routing and Adaptation for Universal Biomedical Image Analysis

· HF Daily Papers ·
OPERA routes biomedical images to specialist models without retraining those experts.

The paper frames expert weight assignment as offline policy learning from a small validation set, then uses test-time adaptation on unlabeled batches. Its agents are calibrated with temperature adjustment, and routing uses agreement and predictive entropy at the instance level. The authors report gains across 9 datasets spanning fundus, X-ray, CT, MRI, and multimodal diagnostics, against more than 30 baselines. Accepted by ACM MM 2026. HF Daily Papers' note

score 4

Categories: Research